Lengthening of mouse hind limbs with local administration of insulin-like growth factor 2
نویسندگان
چکیده
منابع مشابه
Lengthening of mouse hind limbs with local administration of insulin-like growth factor 2.
BACKGROUND For devising potential clinical approaches for limb length discrepancies, we examined local administration of insulin-like growth factor 2 (IGF2). METHODS C57/BL/6 mice (∼ 8 weeks old) were used in this study, and the mice were separated into two groups: an IGF2-treated group and a placebo group. In the IGF2-treated group, IGF2 was locally administered into the distal epiphysis of ...
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Endochondral bone formation observed at the mandibular condyle is regulated by various growth factors including insulin-like growth factor-I (IGF-I). In this paper, we describe a method for the local administration of IGF-I to the bilateral mandibular articular cavities of 3- and 12-week-old rats, and the effects of IGF-I on endochondral bone formation by histomorphometric techniques. In 3-week...
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The aim of the present study was to detect polymorphism in Insulin like growth factor-I (IGF-I) gene of beluga (Huso huso) fish using PCR-SSCP technique and also investigation of its association with growth traits (condition factor, body length and weight). A total of 150 specimens of beluga were randomly selected and DNA was isolated from caudal fin using modified salting out method. Then two ...
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ژورنال
عنوان ژورنال: Journal of the Chinese Medical Association
سال: 2012
ISSN: 1726-4901
DOI: 10.1016/j.jcma.2012.07.009